Heart Failure Research Study
A study of an investigational medication for adults living with heart failure and obesity.
Lupus · Enrolling now
Every DISCOVERY towards progress matters.

About the study
Living with cutaneous lupus erythematosus (CLE) can mean painful rashes, sores, and scarring that can impact how people live their lives.
Today, no medicine is approved specifically to treat CLE. The DISCOVERY Study is evaluating a potential new medicine for adults living with active CLE to learn whether the study medicine is safe and how much it may help people with CLE. Not every participant will receive the study medicine, and no one will be able to know whether they are receiving the study medicine or not. The medicine is not yet approved by the Food and Drug Administration (FDA), and it may not help you. But every study adds to what we understand, and every person who chooses to participate contributes to that understanding.
Other eligibility criteria apply. The study team will review them with you.
The DISCOVERY Study lasts about 14 months and includes about 17 visits.
You may be allowed to continue taking certain regular lupus medicines while participating in the study. The study team will monitor your health and safety throughout the study. In addition to certain allowed regular lupus medicines, for the first 6 months or so, you will get either the study medicine or a placebo (a pill that looks the same but has no medicine in it). Neither you nor your doctor will know which one you get. The study medicine is a pill you take by mouth once a day.
After 6 months in the study, everyone will start getting the real study medicine even those who were getting the placebo before. So for the rest of the study, all participants will take the real study medicine.
There is no cost to you for study-related care or the study medicine. You may be reimbursed for reasonable study-related expenses, such as travel and parking. Transportation assistance to and from the study site may also be provided. You may bring a caregiver with you to your study visits if you’d like and their transportation may also be covered.
Complete the short form. It takes a few minutes and does not commit you to anything.
A study team member contacts you, explains the study in plain language, and answers your questions.
If it sounds right for you, we confirm whether you meet the eligibility criteria.
Apply to participate
Answer four quick questions, leave your details, and a study team member will call you. Or call (415) 343-2600.
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Participate in research
Studies may take place entirely from home or at participating pharmacy and community locations. You do not need health insurance to participate.