At-Home Trials
Clinical trial visits, delivered where patients live.
Home research visits conducted by highly qualified registered nurses, supporting protocol compliance, sample integrity, and visit-window adherence.
Hawthorne delivers in-home clinical trial visits through a nationwide network of highly qualified GCP-trained nurses, with national coverage that reaches patients everywhere, including geographically remote areas. Bringing the visit to the patient's home reduces travel burden, supporting better enrollment and retention, while ensuring protocol compliance, sample integrity, and timely documentation.
Network figures as of October 1, 2026.
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At-home trials in forty seconds.
Clinical research delivered directly where patients live, supported by 2,000+ GCP-trained nurses under one quality system. Distance from the site is not distance from oversight: standardized SOPs and a single quality system hold across all locations.
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What our nurses deliver
Licensed registered nurses, trained to the protocol.
- In-home clinical trial visits performed by licensed registered nurses
- Extensive protocol procedures including IP administration, physical exam, vital sign collection, and other assessments
- Local and central laboratory blood collection, with on-site sample processing, including centrifugation per the central laboratory manual
- Sample packaging and shipment in accordance with the protocol, central laboratory manual, and IATA requirements, with courier and dry ice coordination
- Collection of study-related health information and electronic source data
- The largest national network of skilled sonographers for in-home echo and imaging-related procedures
Delivered where patients live
A 3,000-participant national prevalence study whose echocardiograms were performed in participants’ homes, in all 50 states.
Hawthorne Health supported the Cardiovascular Research Foundation on PREVUE-VALVE. We contacted eligible individuals to obtain informed consent and schedule the study procedures, and our sonographers performed the echocardiograms in participants’ homes, in all 50 states, to the core laboratory’s acquisition protocol.
An independent research organization (Hawthorne Health) then contacted eligible individuals to obtain informed consent and schedule the study procedures.
PREVUE-VALVE, Methods
Earlier prevalence studies drew on people who already had a clinical reason for an echocardiogram, or who were well enough to travel to a medical facility. This one went to the participants instead, and the authors conclude it establishes the feasibility of large-scale decentralized cardiovascular imaging.
The investigators thank Michael Arevelo, Ah’Shirae Arana, and Caroline Callison of Hawthorne Health in the paper’s acknowledgments.
Brener MI, et al. Senior author: Cohen DJ. Population Prevalence of Valvular Heart Disease in the United States: The PREVUE-VALVE Study Journal of the American College of Cardiology. J Am Coll Cardiol. 2026;87(23):3227-3239. doi:10.1016/j.jacc.2026.02.5137 (NCT05357404)
Where we reach
Every state, and who we can reach in it.
In-home visits run in all fifty states. Where we also hold a community site, the map carries the population around it from Census data, so coverage can be checked rather than taken on trust. Select a state.
How visits are managed
Centralized scheduling keeps visits within protocol windows.
All visits are coordinated through our centralized scheduling and visit management platform, designed to keep visits within protocol-defined windows.
- Electronic source data documentation completed accurately, quality-reviewed, and shared securely with the study site within 24 to 48 hours
- Rescheduling and missed visits are proactively rebooked within allowable windows
- A network of on-call nurses supports urgent needs, typically responding within 2 to 4 hours depending on location
- Primary and backup nurses are assigned by geography, and the same nurse is retained across visits where feasible to reduce variability and build patient familiarity
Trained and documented to stand up to review
One quality system, audit-ready records.
Why sponsors use this model
All nurses are licensed in their practicing states and trained in GCP/ICH, HIPAA, Hawthorne SOPs, and study-specific protocol and laboratory requirements. Training completion, delegation, and documentation are maintained in 21 CFR Part 11-compliant systems and available for PI and sponsor review.
National coverage
Urban, rural, and geographically remote areas, including populations traditionally excluded from research.
Improved retention
Reduced patient travel burden supports continued participation.
Visit-window adherence
Supported by centralized scheduling and proactive rebooking.
Consistent documentation
Audit-ready records, quality-reviewed before they reach the site.
Decentralized and hybrid trials
Enabling decentralized and hybrid trials.
Run a study fully decentralized, add a decentralized arm, or bring select visits home in a hybrid design. One network supports all three.
Ways to partnerCardiac imaging
Cardiac imaging, delivered at the patient's home.
Sonographers and centralized cardiology interpretation across all 50 states, for trials and REMS programs.
Cardiac solutionsReview at-home fit for your protocol
Send us your protocol for a feasibility review.
We will come back with a clear view of fit, coverage, and a recommended delivery approach.